Fibres are the materials, which are available in the form of thin, continuous and flexible strands spun into yarn and made into fabrics. Fabrics are defined as a cloth material made by knitting or weaving or of threads together. The Chapter “Fibre and Fabric” has topics related to a variety of fabrics, fibres, plant fibres, Natural Fibres vs Synthetic Fibres and spinning of cotton yarn. After studying this chapter, students will be able to get crucial insights into the process of making fabric from yarn together with the historical aspects of clothing.